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Tablet Coating Overview

Definition of Tablet Coating:Coating is the process of compressing a granulating layer around a pre…

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Pharmacy and therapeutic committee (PTC)

Definition Pharmacy and therapeutic committee (PTC): The PTC is a group of persons which formulate policies regarding therapeutic use of drugs. This committee is composed of physicians, pharmacists & other health professionals with the inclusion of the medical staff. It serves as the communication line between the medical staff & pharmacy department. Other names are Pharmacy Committee, Formulary Committee, Therapeutic committee & PTC. Purposes of Pharmacy and therapeutic committee (PTC): The primary purposes of the P&T committee are 1. Policy Development. The committee formulates policies regarding evaluation, selection, and therapeutic use of drugs and related devices. 2. Education. The committee recommends or assists in the formulation of programs designed to meet the needs of the professional staff (physicians, nurses, pharmacists, and other health-care practitioners) for complete current knowledge on matters related to drugs and drug use. Organizati

Preformulation: Fundamental Aspects for Product Development

Prior to development of any formulations the physiochemical properties of drug molecule should be known to the formulator. Preformulation studies have a significant part to play in anticipating formulation problems and identifying logical path in liquid, semisolid and solid dosage form technology. Prior to the development of pharmaceutical dosage forms, it is essential that be valid fundamental physical and chemical properties of the drug molecule and other divided properties of the drug powder are determined. Preformulation is to make available and realize information regarding: 1) The degradation process 2) Any adverse conditions relevant to the drug 3) Bioavailability 4) Pharmacokinetics and formulation of similar compounds 5) Toxicity. Preformulation influences - a) Selection of the drug candidate itself b) Selection of formulation components c) API and drug product manufacturing processes d) Determination of the most appropriate container closure

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